Maternal prenatal carotenoids and child lung function: exploration of modifying factors.

ABSTRACT:

Background

While childhood airway outcomes have been associated with prenatal nutrition, few studies examined carotenoids, a group of nutrients with antioxidant properties, as potential modifiers.

Objectives

In n=677 mother-child dyads enrolled in the Conditions Affecting Neurocognitive Development and Learning in Early Childhood cohort, we examined associations between prenatal carotenoids (α-carotene, β-carotene, β-cryptoxanthin, lycopene and zeaxanthin) and child lung function at ages 8-9 years. Maternal-child factors that may modify associations were also assessed.

Methods

Second-trimester plasma carotenoid concentrations were assayed and corrected for cholesterol. Outcomes included forced expiratory volume in one second (FEV₁), forced vital capacity (F

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12373145 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature