Global burden of NAFLD 1990-2021 and projections to 2035: Results from the Global Burden of Disease study 2021.

ABSTRACT: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. The global burden of NAFLD is increasing. This study used the Global Burden of Disease (GBD) 2021 study data to assess the burden and development trends of NAFLD from 1990 to 2021. The incidence, prevalence, death and disability-adjusted life years (DALYs) rates of NAFLD in geographic populations worldwide from 1990 to 2021 were extracted from the GBD 2021 study data. The global temporal trend of NAFLD from 1990 to 2021 was evaluated using estimated annual percentage change and age-standardized rate. The Bayesian age-period-cohort model was used to predict NAFLD burden future trends to 2035. The global age standardized incidence rate (ASIR) of NAFLD among the all-age population increased by 25% and the age

SUBMITTER: Mao Y 

PROVIDER: S-EPMC12373163 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature