Nucleated red blood cell count as a novel predictive biomarker for acute kidney injury and prognosis in patients with acute pancreatitis: A retrospective cohort study.

ABSTRACT: Nucleated red blood cells (NRBCs) have been reported to correlate to poor prognosis in critically ill patients. This study aimed to identify the role of NRBC count in early diagnosis of acute kidney injury (AKI) and prediction of poor prognosis in patients with acute pancreatitis (AP). This retrospective cohort study enrolled AP patients who were admitted to our hospital from January 1, 2020 to January 1, 2024. Demographic data, NRBC count, laboratory indicators, and outcomes were recorded. Binary logistic regression analysis was used to identify independent biomarkers for AKI diagnosis and prognosis of AP. Receiver operating characteristic (ROC) curves, net reclassification index (NRI) and integrated discrimination improvement (IDI) were used to evaluate the predictive value of NRBC count

SUBMITTER: Yan QY 

PROVIDER: S-EPMC12373243 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature