Longitudinal study of Orthohantavirus hantanense in Apodemus agrarius and disease risk assessment in the Republic of Korea during 2000-2019.

ABSTRACT: Orthohantavirus hantanense (HTNV) is a zoonotic pathogen transmitted by rodents and the causative agent of hemorrhagic fever with renal syndrome (HFRS) in East Asia. Long-term reservoir population ecology studies have enhanced our understanding of hantavirus infection patterns and support disease risk assessments critical for military and civilian populations in HTNV high-risk areas. Here, we evaluated fluctuations in the population dynamics of Apodemus agrarius, the primary reservoir of HTNV, assessed hantavirus seroprevalence, and conducted a descriptive analysis of HFRS disease risks in the Republic of Korea (ROK). From 2000 to 2019, a total of 12,476 small mammals representing 15 species were captured across locations spanning northern to southern regions. A. agrarius was the most freq

SUBMITTER: Klein TA 

PROVIDER: S-EPMC12373885 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature