Establishing a Multicenter Active Adverse Events Following Immunization Sentinel Surveillance Network Across 22 Tertiary Care Hospitals in India: Protocol for a Prospective Observational Study.

ABSTRACT:

Background

The rapid evolution of immunization programs in low- and middle-income countries (LMICs) has necessitated an augmentation of capacity for postlicensure vaccine safety monitoring.

Objective

This study describes the protocol for establishing a Multicenter Active Adverse Events Following Immunization Surveillance System (MAASS) network in India, which conducted prospective observational surveillance for 12 adverse pediatric outcomes between November 1, 2017, and March 20, 2020.

Methods

A multistage site selection process was implemented, beginning with an initial screening survey followed by in-person visits to assess the suitability of potential tertiary care hospitals for inclusion in the network. We adopted a decentralized, collaborative approach to develop

SUBMITTER: Sharan A 

PROVIDER: S-EPMC12374136 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature