Assessment of PBC Pruritus From the ITCH-E Study: Quality of Life, Productivity, and Treatment Experiences.

ABSTRACT: This US-based study assessed the impact of pruritus on health-related quality of life (HRQoL) and treatment experiences of people with primary biliary cholangitis (PBC). Patients with PBC were recruited from a physician panel and patient advocacy group. Participants were grouped by the Pruritus Numerical Rating Scale (NRS): No/Mild Pruritus (NMP, NRS < 4) and Moderate/Severe Pruritus (MSP, NRS ≥ 4). Participants completed the 5-D Itch, PBC-40, EQ-5D-5L, Chronic Liver Disease Questionnaire (CLDQ-PBC), Work Productivity and Activity Impairment (WPAI), and Functional Assessment of Chronic Illness Therapy - Fatigue Scale, Version 4 (FACIT-Fatigue) questionnaires, and PBC treatment experiences questions. Differences were analysed using regression models for confounders. An MSP group subset resp

SUBMITTER: Levy C 

PROVIDER: S-EPMC12374225 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature