Behavioral variant frontotemporal dementia as a model for understanding the cognitive and cerebral determinants of verbal creativity.

ABSTRACT: Although creativity is an essential cognitive function to adapt to an ever-changing world, its neurocognitive and cerebral bases still need clarification. Current models highlight the interaction between associative and executive processes underpinned by the default mode (DMN), executive control (ECN) and salience networks (SN). Furthermore, recent neuroimaging studies highlight the key role of the prefrontal cortex (PFC), located at the crossroads of these networks. Hence, behavioral variant frontotemporal dementia (bvFTD), characterized by progressive neurodegeneration principally impacting the prefrontal cortex and the intrinsic connectivity of these three creativity-related networks, represents a unique model to study creativity. In this study involving 14 bvFTD patients and 20 matched

SUBMITTER: Altmayer V 

PROVIDER: S-EPMC12374279 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature