Pre- and postoperative predictors of extrahepatic recurrence after curative resection for hepatocellular carcinoma.

ABSTRACT: The factors associated with extrahepatic recurrence (EHR) after curative resection for hepatocellular carcinoma (HCC) have rarely been investigated. This study examined the pre- and postoperative predictors of EHR after curative resection in HCC patients over a ten-year follow-up period. A retrospective review was conducted on treatment-naïve HCC patients who underwent curative resection between 2004 and 2019 at four tertiary hospitals in South Korea. The cohort of 1,069 patients was divided into a derivation cohort (n = 683) and a validation cohort (n = 386) based on participating institutions. In the derivation cohort, the mean age was 59.8 years, and 85.7% were male. The majority of patients (98.7%) had compensated liver cirrhosis, and chronic hepatitis B was the prevalent etiology (72.

SUBMITTER: Lee CH 

PROVIDER: S-EPMC12374353 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature