Association between tonsillectomy plus steroid pulse therapy and renal outcomes in patients with IgA nephropathy: a retrospective cohort study.

ABSTRACT: IgA nephropathy (IgAN) is the most common disorder in chronic glomerulonephritis, and various treatment methods have been established. Tonsillectomy and steroid pulse therapy (TSP) are widely performed in Japan. However, their correlation with renal outcomes remains unclear. In this study, we aimed to examine the association between renal prognosis and steroid pulse therapy with or without tonsillectomy. In this retrospective cohort study, we identified patients diagnosed with IgAN between April 2002 and March 2021 using a Japanese healthcare records database. We selected patients with a prescription history of methylprednisolone for three consecutive days within one year of diagnosis and an estimated glomerular filtration rate (eGFR) of 30 mL/min/1.73 m2 or above. We categorized the patie

SUBMITTER: Hayashi A 

PROVIDER: S-EPMC12374458 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature