Improving chest pain risk assessment: validation of HEART, TIMI, GRACE, EDACS-ADP, and HET for MACE prediction in the emergency department.

ABSTRACT: Chest pain is a common and challenging complaint in emergency departments (EDs), necessitating accurate risk stratification to identify patients at risk for major adverse cardiac events (MACE) while avoiding unnecessary admissions. Several scoring systems have been developed for this purpose, yet their external validity in Middle Eastern populations remains understudied. To compare and validate the prognostic accuracy of HEART, TIMI, GRACE, EDACS-ADP, and HET scoring systems in predicting 6-week MACE among patients with chest pain presenting to two tertiary care centers in Isfahan, Iran. This retrospective cohort study included adult patients (aged > 18 years) who presented with non-traumatic chest pain to two tertiary referral centers in Isfahan between February and June 2024. Patients' c

SUBMITTER: Nasr Isfahani M 

PROVIDER: S-EPMC12374469 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature