Dataset Information
Impact of syndromic molecular diagnostics on antimicrobial adequacy and time to therapy in critically ill patients with pneumonia: a systematic review and meta-analysis of randomized trials.
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ABSTRACT:
SUBMITTER: de Albuquerque Pessoa Dos Santos Y
PROVIDER: S-EPMC12374470 | biostudies-literature | 2025 Aug
REPOSITORIES: biostudies-literature
Publications
Impact of syndromic molecular diagnostics on antimicrobial adequacy and time to therapy in critically ill patients with pneumonia: a systematic review and meta-analysis of randomized trials.
Critical care (London, England) 20250822 1
BACKGROUND: Pneumonia is a leading cause of ICU admission and mortality, requiring prompt and adequate antimicrobial therapy to improve outcomes. Conventional cultures are slow and often insensitive, delaying targeted treatment. Syndromic PCR panels offer rapid identification of pathogens and resistance genes directly from respiratory samples, potentially improving early antibiotic optimization. However, the true clinical benefit of these diagnostics in critically ill patients remains uncertain. ...[more]
