Effect of high-flow nasal oxygen therapy on cardiac cycle efficiency in coronary artery disease patients undergoing endoscopy: study protocol for randomised controlled trial.

ABSTRACT: Patients with coronary artery disease (CAD) have diminished tolerance for gastrointestinal endoscopy procedures (upper/lower) performed under deep sedation, resulting in increased incidence rates of hypotension and myocardial ischaemia among these patients. Avoiding hypoxemia caused by deep sedation and increased oxygen consumption caused by inadequate sedation is particularly important in these patients. Based on recent data indicating that high-flow nasal oxygen therapy (HFNO) is beneficial for preventing hypoxaemia in high-risk patients, this study investigated whether HFNO can improve myocardial oxygen supply during gastrointestinal endoscopy under deep sedation. Using cardiac cycle efficiency (CCE) data from MostCare to assess myocardial oxygen supply-demand balance in patients with C

SUBMITTER: Xie F 

PROVIDER: S-EPMC12374681 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature