Real-World Effectiveness of Rebamipide on Gastritis Symptoms: A Patient-Focused Approach.

ABSTRACT: Rebamipide is a gastric mucosal protectant used to relieve gastritis symptoms. Real-world evidence on the comparative effectiveness of rebamipide monotherapy versus combination therapy with proton-pump inhibitors (PPIs) in routine clinical settings is limited. This study evaluated the effect of rebamipide in reducing subjective gastrointestinal (GI) symptoms among patients with gastritis symptoms using a patient-focused approach. This multicenter, observational study enrolled patients aged 19 years and older who were prescribed rebamipide for gastritis symptoms across 81 local clinics and hospitals. Patients received rebamipide twice daily for 2 weeks, with an optional 4-week extension. GI symptom severity and frequency were collected via patient-reported outcomes at baseline and posttreat

SUBMITTER: Woo HJ 

PROVIDER: S-EPMC12374753 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature