Association between glycemic variability and mortality in critically ill patients with heart failure.

ABSTRACT: Heart failure is a significant global health challenge with high mortality rates. This study examines the association between glycemic variability and short-term mortality in critically ill heart failure patients. Data from the eICU Collaborative Research Database (eICU-CRD) and the Medical Information Mart for Intensive Care (MIMIC-IV) database were analyzed, including 23,744 heart failure patients. Glycemic variability, measured by the coefficient of variation of glucose levels during ICU stay, was categorized into quartiles. Multivariable logistic regression and Cox proportional hazards models were used to assess associations with in-hospital and 30-day mortality. Linear regression models were employed to evaluate the association with ICU length of stay. Dose-response relationships were

SUBMITTER: Liu P 

PROVIDER: S-EPMC12375012 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature