Tracking cancer-related fatigue during chemotherapy: Insights from a comparative cohort study of early breast cancer patients.

ABSTRACT: Cancer-related fatigue (CRF) is a multifactorial symptom commonly experienced by breast cancer patients treated with chemotherapy (CT) that impairs quality of life and may influence cancer recurrence by reducing treatment compliance. This cohort study examined the kinetics of CRF throughout CT in breast cancer patients and determined its relationship with exercise-related variables. One hundred breast cancer patients were included. Three time points were investigated: pre-CT, 8 weeks, and post-CT. Patients were categorized as fatigued or non-fatigued according to their FACIT-F score. Exercise capacity (assessed using the 6-minute walking test), muscle mass and force, neuromuscular fatigue, and physical activity level were measured. Among the seven patterns of CRF trajectories identified, t

SUBMITTER: Mallard J 

PROVIDER: S-EPMC12375849 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature