Project description:We evaluated genome wide expression patterns in wild yellow-bellied marmots (Marmota flaviventris) prior to either dispersing from or remaining philopatric to their natal colony site. We identified differential expression of genes involved in lipid metabolism and muscle generation. Further, we found a network of genes involved in extra-cellular immune function and MHC class II pathways that increased in dispersers. Our results provide novel insights into the fundamental molecular changes required for natal dispersal in vertebrates.