Multipoint Coordinative Capture of Olefinic Substrates Utilizing Metal-Carbon Bonds by Macrocyclic Complex.

ABSTRACT: Terpenoids and unsaturated fatty acids containing C═C double bonds are biologically and synthetically important compounds. The transformation of these substrates catalyzed by proteins relies on precise molecular capture. However, achieving precise molecular recognition of C═C double bonds using synthetically designed hosts remains a significant challenge. We now report a macrocyclic palladium tetranuclear complex that functions as a synthetic receptor featuring coordination sites within its inner cavity. This receptor selectively binds specific double bonds of unsaturated hydrocarbon substrates. Squalene (C₃₀H₅₀), a linear triterpene with chemically similar six isoprenoid units, was captured by the macrocyclic complex through the coordination of four out of the six C═

SUBMITTER: Sugawara K 

PROVIDER: S-EPMC12377451 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature