Remote analysis and management of sweat biomarkers using a wearable microfluidic sticker in adult cystic fibrosis patients.

ABSTRACT: Sweat parameters such as volume and chloride concentration may offer invaluable clinical insights for people with CF (PwCF). Pilocarpine-induced sweat collection for chloridometry measurement is the gold standard for a CF diagnosis, but this technique is cumbersome and not suitable for remote settings or repeat measurements. We have previously reported the utility of a skin-interfaced microfluidic device (CF Patch) in conjunction with a smartphone image processing platform that enables real-time measurement of sweating rates and sodium chloride loss in laboratory and remote settings. Here, we conducted clinical studies assessing the accuracy of the CF Patch compared to chloridometry when using pilocarpine to induce sweat. We also tested the feasibility and accuracy of exercise-induced swea

SUBMITTER: Nelson RS 

PROVIDER: S-EPMC12377746 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature