Genomic diversity of uropathogenic Escherichia coli in clinical isolates from six latin american countries, 2018-2023.

ABSTRACT:

Background

Motivation for the study. To contribute to the genomic surveillance of UPEC in clinical samples from Latin America, in response to the growing public health problem represented by UTIs and their resistance to antimicrobials. Main findings. Our study revealed a high frequency of high-risk clones, such as ST131 and ST1193. Critical mutations were identified in genes associated with resistance to multiple antibiotics, including fluoroquinolones, beta-lactams, and fosfomycin. Implications. Our results highlight the urgent need to strengthen UPEC surveillance in Latin America. Tracking resistant strains and implementing measures to limit their spread is crucial and has a significant impact on the effectiveness of available treatments.

Objective.

To genetically characte

SUBMITTER: Caballero F 

PROVIDER: S-EPMC12377891 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature