A positive resection margin does not determine long-term survival following colorectal liver metastasis resection.

ABSTRACT:

Backgrounds/aims

This study evaluates whether positive resection margins after colorectal liver metastasis (CRLM) surgery are linked to tumor recurrence and impact long-term survival.

Methods

The oncological outcomes of patients undergoing curative resection for CRLM at a single institution were analyzed concerning clinicopathological factors using both univariate and multivariate statistical methods.

Results

Among 138 patients who underwent liver resection for CRLM, hepatic tumor recurrence was noted in 70 patients (50.7%), with no significant difference between those with R0 and R1 resections (p = 0.33). Positive resection margins were associated with tumor proximity to major liver vascular structures, while negative margins corresponded more frequently with

SUBMITTER: Konstantinou A 

PROVIDER: S-EPMC12377995 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature