Outcome and Prognostic Factors of Dogs Treated for Infiltrative Lipoma Undergoing Radiation Therapy: A Retrospective Multi-Institutional Study of 29 Cases.

ABSTRACT: Canine infiltrative lipomas are localised and invasive tumours that are commonly treated with surgery and/or radiation therapy (RT). There is limited efficacy data for treatment of infiltrative lipomas, and optimal fractionation strategies remain unclear. We retrospectively assessed the outcomes and prognostic factors in a cohort of dogs that underwent intensity modulated or three-dimensional conformal RT for infiltrative lipoma. Twenty-nine dogs were included from four academic institutions. The median total radiation dose prescribed and delivered was 51 Gy (range = 20-57 Gy). Dose per fraction ranged from 2.4 to 4.2 Gy, with a median of 3 Gy. Median progression-free survival (PFS) was 1483 days; the median overall survival (OS) was 1483 days. Disease progression was documented in four do

SUBMITTER: Matsuyama A 

PROVIDER: S-EPMC12378080 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature