Pterygomandibular raphe invasion as a novel grading and prognostic factor for squamous cell carcinoma of buccal mucosa: a retrospective study with propensity score matching.

ABSTRACT:

Background

Squamous cell carcinoma of the buccal mucosa (SCCBM) is a prevalent malignancy of the oral cavity with high morbidity and mortality rates. The pterygomandibular raphe (PMR) connects the oral cavity, pharynx, and masticator space, serving as a key anatomical landmark during surgical resection. However, PMR invasion into SCCBM remains poorly understood. This study assessed the prognostic significance of PMR invasion in patients with resectable SCCBM.

Methods

The study included 82 patients with SCCBM, excluding those with T4b, who underwent radical resection at Kumamoto University Hospital between 2000 and 2017. Patients were categorized into three groups based on PMR invasion patterns: non-contact, contact, and invasion. The relationship between PMR invasion and cli

SUBMITTER: Yoshida R 

PROVIDER: S-EPMC12378123 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature