Unknown

Dataset Information

0

Dual T/NK cell engagement via B7-H6-targeted bispecific antibodies and IL-15 eradicates chemo-resistant solid tumors

ABSTRACT:

SUBMITTER: Ma X 

PROVIDER: S-EPMC12378318 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature

Json Xml

Similar Datasets

Unknown Affinity Maturation of B7-H6 Translates into Enhanced NK Cell-Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement.
| S-EPMC7750860 | biostudies-literature
Unknown Nanoenabled IL-15 Superagonist via Conditionally Stabilized Protein-Protein Interactions Eradicates Solid Tumors by Precise Immunomodulation.
| S-EPMC11613988 | biostudies-literature
Unknown B7-H6-mediated downregulation of NKp30 in NK cells contributes to ovarian carcinoma immune escape.
| S-EPMC4485754 | biostudies-literature
Unknown Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
| S-EPMC6441079 | biostudies-literature
Unknown Enhanced ADCC and NK Cell Activation of an Anticarcinoma Bispecific Antibody by Genetic Insertion of a Modified IL-15 Cross-linker.
| S-EPMC5088765 | biostudies-literature
Unknown Secreted Ligands of the NK Cell Receptor NKp30: B7-H6 Is in Contrast to BAG6 Only Marginally Released via Extracellular Vesicles.
| S-EPMC7926927 | biostudies-literature
Unknown Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20.
| S-EPMC5561058 | biostudies-literature
Unknown NK Cell IL-10 Production Requires IL-15 and IL-10 Driven STAT3 Activation.
| S-EPMC6736993 | biostudies-literature
Unknown IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction.
| S-EPMC5954038 | biostudies-literature
Unknown Robust differentiation of NK cells from MSLN.CAR-IL-15-engineered human iPSCs with enhanced antitumor efficacy against solid tumors.
| S-EPMC12047432 | biostudies-literature