Intraventricular pressure difference estimation based on blood speckle tracking-invasive validation and early clinical application.

ABSTRACT:

Aims

Ventricular relaxation creates an intraventricular pressure difference (IVPD) and resultant diastolic suction. Non-invasive estimation by echocardiographic techniques would allow to clinically evaluate IVPD as an important component of diastolic functional assessment. The aims of the current study were to evaluate the accuracy of IVPD estimation based on Blood Speckle Tracking (BST) echocardiography compared with invasive pressure measurements and to clinically apply the method in children with univentricular hearts (UVH) and controls.

Methods and results

The accuracy of BST-based IVPD-estimates was assessed in an open-chest porcine model, comparing BST-based IVPD with simultaneous repeated invasive pressure measurements in six pigs using micromanometer catheters. BST-b

SUBMITTER: Sorensen K 

PROVIDER: S-EPMC12378583 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature