High throughput tear proteomics with data independent acquisition enables biomarker discovery in allergic conditions.

ABSTRACT: The search for pathological biomarkers in biological fluids that can provide valuable insight into an individual's health status, is a relevant area of research for multiple pathologies. Currently, the use of proteomics for the identification of differences in protein expression profiles between samples from healthy subjects and patients, has emerged as a powerful strategy to improve the current diagnosis of various pathologies or propose novel therapeutic approaches. Among the biological fluids from which new pathological biomarkers can be identified, tear secretion is highly attractive, since it can be collected non-invasively and could better concentrate proteins that sensitively reflect allergic responses, owing to their exposure to environmental factors and its connection to the respi

SUBMITTER: Vera-Montecinos A 

PROVIDER: S-EPMC12379103 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature