The Baeyer-Villiger Oxidation of Cubyl Ketones: A Synthetic Route to Functionalized Cubanols.

ABSTRACT: The synthesis of functionalized cubanols has been developed via a 2-step protocol comprising of a Baeyer-Villiger oxidation of cubyl ketones, followed by acid hydrolysis. As part of this study, we determine the relative migratory aptitude of cubyl groups in the Baeyer-Villiger oxidation and rationalize these experimental findings with computational studies.

SUBMITTER: Hind J 

PROVIDER: S-EPMC12379164 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature