Isolation of porcine intestinal Lactobacillus salivarius and antimicrobial potential of its biosurfactant.

ABSTRACT:

Background

Lactobacillus salivarius (L. salivarius) is a probiotic widely colonized in the gastrointestinal tracts of humans and animals. Its biosurfactant (BS) exhibits antibacterial and antiviral activities, along with advantages such as biodegradability, non-toxicity, and stability. Porcine circovirus type 2 (PCV2) is a major pathogen in swine farms, causing immunosuppression or immune dysfunction. PCV2-positive herds exhibit elevated susceptibility, often accompanied by severe secondary bacterial infections. To explore novel antimicrobial biologics for enhancing swine immunity, this study isolated a biosurfactant-producing Lactobacillus strain from the intestines of PCV2-infected piglets using the calcium carbonate plate method, and analyzed the anti-microbial activity of the b

SUBMITTER: Zhou X 

PROVIDER: S-EPMC12379379 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature