Association of exercise-induced pulmonary hypertension with nailfold capillary density in systemic sclerosis: a single-center retrospective observational study.

ABSTRACT: Exercise-induced pulmonary hypertension (exercise PH) is instrumental in the early detection of pulmonary arterial hypertension. However, the prevalence and specific characteristics of exercise PH in systemic sclerosis (SSc), as well as factors that might facilitate its identification, remain inadequately understood. We investigated the clinical profiles of SSc patients diagnosed as PH, exercise PH, or non-PH. This study included 50 patients with SSc and exercise intolerance. We compared the physical examination findings, biochemistry tests, echocardiography, respiratory function tests, and resting and exercise right heart catheterization outcomes of the PH, exercise PH, or non-PH groups. In a cohort of 50 patients with SSc and exercise intolerance, 30.0% were diagnosed with PH, and 44.0%

SUBMITTER: Kusaka K 

PROVIDER: S-EPMC12379380 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature