The diagnostic role of exploratory eye movement in schizophrenia: a systematic review and meta-analysis.

ABSTRACT: Exploratory eye movement (EEM) parameters, such as the number of eye fixations (NEF), the responsive search score (RSS), and the discriminant index (D score), serve as reliable biomarkers unaffected by medication or disease progression. However, the diagnostic accuracy of these parameters remains uncertain due to inconsistent thresholds and limited validation in small-sample studies. This study aimed to explore reliable diagnostic thresholds for NEF, RSS and D score values for clinical use. Eight databases were used to identify relevant studies with tailored search strategies. Two independent reviewers screened all retrieved literatures according to pre-defined inclusion and exclusion criteria. Key information of included studies was extracted in standardized tables. Diagnostic Accuracy-2

SUBMITTER: Dong Z 

PROVIDER: S-EPMC12379402 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature