Enzymatic cottonseed protein alleviates DSS-induced enteritis in juvenile yellow catfish (Pelteobagrus fulvidraco): focus on macrophage polarization and necroptosis in the intestine.

ABSTRACT: In intensive aquaculture systems, the frequent incidence of enteritis reduces production efficiency and results in significant economic losses. Protein feeds account for 40%-60% of aquafeed expenses, and with the growth of intensive aquaculture, demand for fishmeal as a key protein source outstrips supply, driving up prices. This study investigated the therapeutic potential of reducing dietary protein levels by 3% and adding enzymatic cottonseed protein (ECP) in juvenile yellow catfish with dextran sulfate sodium (DSS)-induced enteritis. A total of 1,260 healthy juvenile yellow catfish (Pelteobagrus fulvidraco), with an average body weight of 5.90 ± 0.05 g, were randomly allocated into 7 experimental groups, each with 3 replicates. The fish were fed one of seven diets for 10 weeks: a norma

SUBMITTER: Zhang G 

PROVIDER: S-EPMC12379407 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature