The effect of probiotics on weight management in patients with severe obesity undergoing metabolic and bariatric surgery: a systematic review and meta-analysis.

ABSTRACT: Although metabolic and bariatric surgery (MBS) remains an effective intervention for severe obesity, postoperative weight regain persists as a significant clinical challenge. Probiotics have emerged as a potential adjunct therapy to optimize outcomes, but their efficacy in weight management remains controversial. This meta-analysis evaluates the effect of probiotics supplementation on weight management in patients following MBS. A comprehensive search strategy was executed across four databases (PubMed, Embase, Scopus and Cochrane Library) from inception to April 10th, 2025. Inclusion criteria encompassed randomized controlled trials comparing probiotics with placebo in patients with severe obesity undergoing MBS. Primary outcomes including percent excess weight loss (%EWL), postoperative

SUBMITTER: Wang S 

PROVIDER: S-EPMC12379696 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature