Role of Adjuvant Chemotherapy in Distal Cholangiocarcinoma.

ABSTRACT:

Background

Recent studies addressing the role of adjuvant chemotherapy (AC) in cholangiocarcinoma (CCA) have been published; however, there are challenges in generalizing the findings due to different prognostic characteristics depending on tumor location and resectability. Therefore, this study aimed to investigate the role of AC in distal cholangiocarcinoma (dCCA), a common tumor subtype of CCA.

Method

Data from 497 patients with dCCA who underwent curative surgery at Seoul National University Hospital between 2000 and 2019 were reviewed using prospectively collected clinicopathologic information.

Results

The median overall survival (OS) and recurrence-free survival (RFS) in the entire cohort were 62.9 and 44.0 months, respectively. AC was associated with improved f

SUBMITTER: Chae YS 

PROVIDER: S-EPMC12380034 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature