Neural representations in MPFC and insula encode individual differences in estimating others' preferences.

ABSTRACT: In human society, successful social interactions often hinge upon the ability to accurately estimate other's perspectives, a skill that necessitates integrating contextual cues. This study investigates the neural mechanism involved in this capacity through a preference estimation task. In this task, participants were presented with the target's face and asked to predict their preference for a given item. Preference estimation accuracy was assessed by calculating the percentage of correct guesses, where participants' responses matched the target's preferences on a 4-point Likert scale. Our research demonstrates that, based on inter-subject representational similarity analysis (IS-RSA), the multi-voxel patterns in the medial prefrontal cortex (mPFC) and the anterior insula (AI) predict indiv

SUBMITTER: Kang H 

PROVIDER: S-EPMC12380472 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature