The microRNA pathway regulates obligatory aestivation in the cabbage stem flea beetle Psylliodes chrysocephala.

ABSTRACT: Aestivation, or summer diapause, is a dormancy strategy that enables animals to survive hot and dry summer conditions. Despite its ecological importance, the gene regulatory mechanisms underlying aestivation remain poorly understood. MicroRNAs (miRNAs) are post-transcriptional regulators involved in various biological processes, including development. Here, we investigated the role of miRNAs in obligatory aestivation in the cabbage stem flea beetle (Psylliodes chrysocephala), a major pest of oilseed rape. Small RNA sequencing revealed that approximately 25% of miRNAs were differentially abundant during aestivation. RNA interference-mediated inhibition of the miRNA pathway, combined with proteomics, identified 116 miRNA-regulated proteins involved in metabolic and catabolic processes. Integ

SUBMITTER: Guney G 

PROVIDER: S-EPMC12381080 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature