Primary neuroendocrine tumors of the breast according to the WHO 2019 classification; real life experiences of rare tumor types of the breast.

ABSTRACT:

Background

Neuroendocrine neoplasms (NEN) originate in many body parts, with 70% reported from the gastrointestinal system, 25% from the lungs. NENs of the breast account for < 1% of all NENs. The primary breast NEN nomenclature was changed in the most recent World Health Organization classification in 2019. Since the pathological classification has changed several times, there are no definitive data on treatment management.

Methods

In this study, patients followed up in our clinic were pathologically reevaluated according to the latest classification.

Results

The clinical characteristics, treatments, recurrence, and survival status of 36 patients with early stage primary breast NEN were examined. A statistically significant difference was determined in respect of ove

SUBMITTER: Sali S 

PROVIDER: S-EPMC12381419 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature