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Progestin-only contraception and thrombosis: An updated systematic review.


ABSTRACT:

Objectives

Evidence is limited on whether the use of progestin-only contraception (POC) is associated with the risk of thrombosis. Our objective was to update an earlier systematic review on POC and thrombosis risk.

Methods

We searched for articles that examined risk of venous thromboembolism (VTE) (e.g., deep venous thrombosis or pulmonary embolism) or arterial thromboembolism (ATE) (e.g., myocardial infarction or stroke) among women with thrombogenic conditions or characteristics or in the general population using POC, compared with women using nonhormonal or no contraception, published during February 1, 2016 through November 30, 2022. We also included articles from a previous systematic review, with articles published through January 2016. We assessed quality for each st

SUBMITTER: Tepper NK 

PROVIDER: S-EPMC12381897 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature