Topographic Features in Retinopathy of Prematurity With en Face Ultra-Widefield OCT.

ABSTRACT:

Purpose

This study presents 2 methods of en face visualization enabled by ultra-widefield (UWF) OCT, which provide topographic information of retinopathy of prematurity (ROP) without requiring direct visualization of cross-sectional scans.

Design

Evaluation of diagnostic technology.

Subjects

Infants undergoing ROP screening at Oregon Health Science University between June 2023 and October 2024, who consented to research imaging.

Methods

An investigational contact-based UWF-OCT captured 800 × 800 A-scans. Max intensity projections (MIP) were constructed, from the highest intensity pixel in each A-scan's x-y coordinate plane. Retinal thickness maps (RTMs) were generated by first segmenting the retina with a previously trained U-net, then calculating the retinal t

SUBMITTER: Sutter DA 

PROVIDER: S-EPMC12381962 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature