Acclimation of Synechocystis sp. PCC 6803 to Alkaline pH Under Ambient Air.

ABSTRACT: Cyanobacteria can thrive at a wide pH range from neutral up to pH 11 depending on the species. Even though cyanobacteria are alkaliphilic, only limited information on the metabolic acclimation to alkaline pH is available. In this study, we conducted a mass-spectrometry-based comparative proteomic analysis of Synechocystis sp. PCC 6803 grown in BG-11 medium buffered at pH 7.5, pH 8.2, and pH 9.2 under ambient air. When comparing cells grown at pH 8.2 to those at pH 7.5, only minor changes in the proteome were observed, with most of the altered proteins originating from the plasma membrane. However, when comparing cells grown under pH 9.2 to those at pH 7.5, a total of 235 proteins were differentially expressed. Synechocystis cells growing at pH 9.2 seem to display a different composition of

SUBMITTER: Mustila H 

PROVIDER: S-EPMC12382314 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature