HBV infection, liver enzymes and their association with adverse liver disease and all-cause death: a matched retrospective cohort study in Eastern China.

ABSTRACT: China has historically been a high-prevalence area for hepatitis B virus (HBV) infection, leading to a high incidence of adverse liver diseases and significant disease burden. However, comprehensive data on HBV infection and associated adverse liver diseases in the Chinese population remain limited. This study aimed to analyse the risk factors for adverse liver outcomes in patients who tested positive for hepatitis B surface antigen (HBsAg). A matched retrospective cohort study was conducted from 1 January to 30 September 2013 in Jiangshan and Shiqi towns in Yinzhou District, Ningbo, Zhejiang Province. Data were sourced from the Yinzhou Health Information System. HBsAg-positive patients were matched 1:2 by birth year, sex, town and calendar period with HBsAg-negative controls. Adverse live

SUBMITTER: Yin Y 

PROVIDER: S-EPMC12382557 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature