Eco-Friendly Silver Nanoparticles Synthesis Method Using Medicinal Plant Fungal Endophytes-Biological Activities and Molecular Docking Analyses.

ABSTRACT: The integration of nanotechnology and green synthesis strategies provides innovative solutions in biomedicine. This study focuses on the biofabrication of silver nanoparticles (AgNPs) using Corynespora smithii, an endophytic fungus isolated from Bergenia ciliata. The eco-friendly synthesis process employed fungal extracts as reducing and stabilizing agents thereby minimizing the need for hazardous chemicals. The AgNPs demonstrated strong potent biological activities, showcasing significant antioxidant, antibacterial, and anticancer properties. The antibacterial efficacy was demonstrated against various Gram-positive and Gram-negative bacteria, while cytotoxicity on the A549 lung cancer cell line revealed an IC₅₀ value of 10.46 µg/mL. A molecular docking analysis re

SUBMITTER: Chandra H 

PROVIDER: S-EPMC12383769 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature