Bifunctional TiO₂@AgNP Superstructures as a SERS-Sensing Platform for Identifying Flavonoids in Chinese Herbal Medicine.

ABSTRACT: Acanthopanax senticosus is an essential medicinal herb in traditional Chinese medicine, with its pharmacological properties largely attributed to bioactive flavonoids. The types and amounts of these flavonoids act as vital quality markers for both the raw materials and the resultant products. In this work, we introduce a TiO2@AgNP nanocomposite designed as a surface-enhanced Raman scattering (SERS) sensor aimed at the preliminary quantification and identification of flavonoids. This is achieved by leveraging the effective molecular adsorption properties of TiO2 alongside the 'hot spots' generated by AgNPs. By optimizing SERS performance through adjustment of the molar ratio between TiO2 and Ag, we can quantitatively evaluate four flavonoids-luteolin, kaempferol, quercetin, and rutin-with l

SUBMITTER: Li Y 

PROVIDER: S-EPMC12384181 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature