Enzyme-Free Monitoring of Glucose Using Molecularly Imprinted Polymers and Gold Nanoparticles.

ABSTRACT: This work describes a non-enzymatic electrochemical glucose biosensor combining for the first time molecularly imprinted polymers (MIPs) for glucose concentration and gold nanoparticles (AuNPs) on screen-printed carbon electrodes (SPEs), where both MIPs and AuNPs were assembled in situ. Electrochemical impedance spectroscopy (EIS) was used to evaluate the analytical performance of the sensor, which has a linear range between 1.0 µM and 1.0 mM when standard solutions are prepared in buffer. Direct measurement of glucose was performed by chronoamperometry, measuring the oxidation current generated during direct glucose oxidation. The selectivity was tested against ascorbic acid and the results confirmed a selective discrimination of the electrode for glucose. Overall, the work presented here

SUBMITTER: Cardoso ARA 

PROVIDER: S-EPMC12384395 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature