An Amperometric Enzyme-Nanozyme Biosensor for Glucose Detection.

ABSTRACT: Amperometric biosensors, due to their high sensitivity, fast response time, low cost, simple control, miniaturization capabilities, and other advantages, are receiving significant attention in the field of medical diagnostics, especially in monitoring blood glucose levels in diabetic patients. In this study, an amperometric glucose biosensor based on immobilized enzyme glucose oxidase (GOx) and bimetallic platinum cobalt (PtCo) nanoparticles was developed. The PtCo nanoparticles, deposited on a graphite rod electrode, exhibited peroxidase-like catalytic properties and were able to electrocatalyze the reduction of H2O2. After immobilization of the GOx, an amperometric signal generated by the biosensor was directly proportional to the glucose concentration in the range of 0.04-2.18 mM. The b

SUBMITTER: Kausaite-Minkstimiene A 

PROVIDER: S-EPMC12384605 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature