Bedside Risk Scoring for Carbapenem-Resistant Gram-Negative Bacterial Infections in Patients with Hematological Malignancies.

ABSTRACT: This study aimed to create a 'carbapenem resistance score' with the risk factors of carbapenem-resistant Gram-negative bacterial infections (GNBIs) in patients with hematological malignancies. Patients with carbapenem-resistant and susceptible GNBIs were included in this study and compared in terms of risk factors. Three models of "carbapenem resistance risk scores" were created with statistically significant variables. The study included 154 patients with hospital-acquired GNBIs, of whom 64 had carbapenem-resistant GNBIs and 90 had carbapenem-susceptible GNBIs. Univariate and multivariate analyses identified several statistically significant risk factors for carbapenem resistance, including transfer from another hospital or clinic (p = 0.038), prior use of antibiotics like fluoroquinolone

SUBMITTER: Basaga SM 

PROVIDER: S-EPMC12385919 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature