Development of Water-Dispersible CuS Nanoparticles for Chemo-Photothermal Therapy and Photoacoustic Application.

ABSTRACT: Photothermal therapy (PTT) is a promising treatment option for cancer. However, biocompatibility, water dispersibility, and good photoresponsiveness are necessary for photothermal agents to be used in PTT. Herein, a soft chemical approach is reported for the design and development of phosphorylethanolamine-functionalized CuS nanoparticles (PEA-CuS NPs) using phosphorylethanolamine (PEA) as a surface passivation agent for combinatorial chemo-photothermal therapy. X-ray diffraction and transmission electron microscopy analyses proved the successful formation of the green covellite CuS phase with an average particle size of 13 nm, while Fourier transform infrared spectroscopy and light scattering measurements demonstrated their surface functionalization with the PEA ligand. The PEA-CuS NPs ha

SUBMITTER: Gupta S 

PROVIDER: S-EPMC12388176 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature