Candidemia: An Update on Epidemiology, Risk Factors, Diagnosis, Susceptibility, and Treatment.

ABSTRACT: Candidemia is a highly prevalent invasive fungal infection caused primarily by C. albicans, C. parapsilosis, C. glabrata (currently Nakaseomyces glabratus), C. tropicalis, and C. krusei (currently Pichia kudriavzevii). Risk factors for the development of candidemia include steroid-induced immunosuppression used in solid organ or hematopoietic transplantation, and neutropenia secondary to infectious or tumorous processes. Alterations in the gut microbiota in people living with HIV, caused by antiretroviral therapy, increase the possibility of colonization by C. albicans. Likewise, the presence of a central venous catheter, parenteral nutrition, and abdominal surgery stand out as the main risk factors for the development of candidemia.

SUBMITTER: Cabrera-Guerrero JP 

PROVIDER: S-EPMC12389578 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature