Effect of Botulinum Toxin on Sensori-Motor Integration in Movement Disorders: A Scoping Review.

ABSTRACT: Background: The primary effect of Botulinum toxin (BoNT) is to cause weakness in the injected muscles by inhibiting the release of acetyl choline from presynaptic nerve terminals. Its effect on sensorimotor integration (SMI) has largely been confined to small studies. The aim of this review is to highlight effect of BoNT on SMI in the context of Parkinson's disease (PD), Cervical dystonia (CD), and Writer's cramp (WC). Methods: Using keywords "Botulinum toxin" and "sensorimotor integration" or "Freezing of gait (FOG)" or 'Tremor"or "Cervical dystonia" or "Parkinson's disease", or "Writer's cramp", PubMed database was searched for relevant articles supporting our view. The abstracts of all resultant articles (case reports, case series, randomized trials, observational studies) were reviewed

SUBMITTER: Das A 

PROVIDER: S-EPMC12390325 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature