Global burden and risk factors of type 2 diabetes mellitus from 1990 to 2021, with forecasts to 2050.

ABSTRACT:

Background

Type 2 diabetes mellitus (T2DM) presents a substantial strain on global healthcare systems. This study seeks to offer robust scientific evidence for the effective prevention and management of T2DM globally through a comprehensive analysis of the disease's burden, trends, and risk factors from 1990 to 2021, as well as future trajectories from 2022 to 2050.

Methods

Data for this study were sourced from the 2021 Global Burden of Disease (GBD) study. T2DM burden was assessed through incidence, prevalence, mortality, and disability-adjusted life years (DALYs), stratified by age, sex, sociodemographic index (SDI), 21 GBD regions, and 204 countries/territories. Trends from 1990 to 2021 were quantified by estimating annual percentage changes. Decomposition analysis identi

SUBMITTER: Huang Q 

PROVIDER: S-EPMC12390814 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature