Cardiovascular Disease as a Predictor of Dementia: A Cross-National Ecological Study of 204 Countries.

ABSTRACT:

Background and aims

Cardiovascular disease (CVD) and dementia represent two of the most pressing global health challenges, particularly in low- and middle-income countries (LMICs). While vascular pathology is increasingly recognized as a contributor to cognitive decline, few studies have systematically explored the global association between CVD and dementia using standardized, population-level data. This study aimed to investigate the relationship between CVD and dementia incidence across 204 countries, stratified by economic status, development level, and geographic region.

Methods

Age-standardized incidence rates for cardiovascular disease (CVD) and dementia in 2021 were sourced from the Global Burden of Disease Study. To examine global and regional associations, bivariat

SUBMITTER: You W 

PROVIDER: S-EPMC12391024 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature