Developing a risk prediction model for sudden cardiac death in children with hypertrophic cardiomyopathy.

ABSTRACT:

Objective

This study aimed to develop a predictive model for sudden cardiac death (SCD) in children with hypertrophic cardiomyopathy (HCM).

Methods

The retrospective study included children diagnosed with HCM who visited Beijing Children's Hospital, Capital Medical University between January 2006 and August 2022. Cox regression analysis was used to identify risk factors for SCD. A nomogram was constructed based on risk factors identified through multivariate analysis.

Results

A total of 184 children (115 boys and 69 girls) were included in the study. The median (IQR) age at the initial diagnosis was 4.54 (0.50-10.25) years. Of these, 141 children were diagnosed with primary HCM, while 43 had secondary HCM. The multivariate analysis showed that age <1 year [hazard rati

SUBMITTER: Zhen Z 

PROVIDER: S-EPMC12391110 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature